Cialis®, which contains the active ingredient tadalafil, is a popular medication that’s prescribed as a treatment for erectile dysfunction, or ED.
Available for use as needed and as a daily treatment for erectile dysfunction, Cialis can provide lasting relief from erectile dysfunction symptoms, allowing you to enjoy more satisfying, fulfilling sex without having to worry about losing your erection.
Like other medications for the treatment of erectile dysfunction, Cialis — and its generic version, tadalafil — can cause adverse effects.
Most side effects of Cialis are mild and transient. However, there are a few side effects that you should be aware of before starting treatment, as well as drug interactions that could occur when Cialis is used with other medications.
Below, we’ve explained what Cialis is, as well as how it works as a treatment for ED. We’ve also listed common and uncommon side effects of Cialis to help you understand what to expect while using this ED medication.
What Is Cialis Used For?
Before we go into detail on specific side effects, let’s quickly go over the basics of what Cialis is and how it works as a treatment for ED.
Cialis® is an FDA-approved medication for erectile dysfunction. It’s currently the longest-lasting erectile dysfunction medication that’s available, providing effects that can last for up to 36 hours per dose.
Viagra®, in comparison, typically lasts around four hours. The long-lasting effects of Cialis have earned it the nickname of the “weekend” ED pill.
Like other erectile dysfunction treatments, Cialis belongs to a class of medications referred to as phosphodiesterase type 5 inhibitors, or PDE5 inhibitors.
Cialis and other PDE5 inhibitors work by increasing blood flow to the erectile tissue that’s found inside your penis. When you’re sexually aroused, blood flows into this tissue more easily, which can make it easier to get and maintain an erection.
Cialis is a safe and effective medication for most men, and it’s widely used in the United States and around the world by men of all ages and backgrounds.
So, what is Cialis used for, aside from ED? Tadalafil, the active ingredient in Cialis, is also used to treat a condition called benign prostatic hyperplasia, or BPH.
Additionally, tadalafil is also sold under the brand name Adcirca® as a medication for managing pulmonary arterial hypertension (PAH), a form of high blood pressure that can affect the arteries in the lungs.
What Are The Side Effects of Cialis?
Like other prescription drugs, Cialis can cause side effects. Most of the side effects of Cialis are mild and temporary, meaning they’ll fade away as Cialis exits your body.
However, there are also several more severe potential side effects of Cialis that, although highly uncommon, are important to know about.
Cialis and tadalafil contain the same active ingredient and work in the same way. As such, both medications have the potential to cause the same side effects and drug interactions.
Below, we’ve listed common and uncommon potential side effects of Cialis and tadalafil, as well as information on how frequently these side effects occur and what you can do to minimize your risk of being affected.
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The Most Common Side Effects of Cialis
Cialis has several common side effects, many of which also occur with other drugs used to treat erectile dysfunction.
This means that if you experience a certain side effect while using Cialis, you may also develop the same issue with medications like sildenafil (generic Viagra), vardenafil (Levitra®) or avanafil (Stendra®).
Headaches
Headaches are a common side effect of all ED medications, including Cialis. In fact, headaches are among the most frequently reported adverse effects of tadalafil, making an appearance in all clinical trials of this medication.
Cialis is a vasodilator, which means it improves blood flow throughout your body, including to the erectile tissue of your penis. By causing your blood vessels to dilate, Cialis can put pressure on nerves in your head, increasing your risk of developing a headache.
Most of the time, Cialis headaches are fairly mild. They typically become less intense over time, although Cialis’s long half-life means that a dull headache might continue for several hours after you use this medication.
According to a 2008 review of studies on tadalafil, 15 percent of men who use this medication at its highest recommended dose (20mg) experience headaches.
Headaches can still be common for those who take a lower 10mg dose of Cialis, affecting about 12 percent of men.
If you’re prone to headaches after taking Cialis, our guide to treating headaches from ED drugs may help. It lists several effective techniques for managing this side effect, from adjusting your dosage to using over-the-counter pain relief medication.
Dyspepsia (Indigestion and/or Heartburn)
Cialis can cause a range of digestive side effects, including indigestion. This is one of the most common side effects of tadalafil, affecting about eight percent of users at 10mg dosage and 10 percent of users at a higher 20mg dose.
Indigestion is a common side effect of all ED medications, not just Cialis. It occurs as a result of the effects of PDE5 inhibitors on smooth muscle tissue in your body.
When you take Cialis, it could cause your lower esophageal sphincter (the part of your body that controls the flow of your stomach contents) to relax. This may lead to heartburn as stomach acid travels from your stomach upward into your esophagus.
For example, researchers have found that sildenafil, the active ingredient in the similar ED drug Viagra, produces a noticeable decrease in lower esophageal sphincter pressure.
If you develop acid reflux, an upset stomach or other digestive issues after taking Cialis, making some small changes to your habits can make this side effect easier to deal with.
Most of the time, you should be able to manage any stomach upset by drinking more water and using over-the-counter antacid medication.
If you experience this side effect often, you may want to consider discussing your Cialis dosage with your healthcare provider. They may adjust your dosage or suggest other changes that you can make to your use of this medication to reduce the severity of this side effect.
Back Pain
Cialis can cause back pain. Approximately three to six percent of Cialis users develop back pain, and the discomfort tends to occur around 12 to 24 hours after taking the medication.
Many people who experience back pain from Cialis report that it usually fades on its own within 48 hours.
Mild to moderate back pain from Cialis can be treated using over-the-counter pain relief. If you experience severe back pain after using Cialis, it’s important to talk to your healthcare provider about adjusting your dosage or switching to another ED medication.
Muscle Aches
Like Viagra and other ED medications, a small percentage of men who use Cialis experience myalgia, or pain that involves your muscles, ligaments, tendons and/or fascia.
In clinical trials of Cialis, approximately one to four percent of men reported muscle pain as an adverse effect, with this side effect more common in men prescribed tadalafil at a dosage of 10 or 20mg.
Muscle aches from Cialis or other ED medications are typically mild and tend to only last while the medication is active in your body.
If you experience pain or discomfort after taking Cialis that’s more than just a faint annoyance, it’s important to talk about this with your healthcare provider.
Facial Flushing
Because Cialis causes your blood vessels to dilate, it might temporarily give you a red, flushed appearance, especially around your nose, cheeks, chin and forehead. This side effect, which is referred to as flushing, can also occur elsewhere on your face and body.
Around three percent of men who use Cialis experience facial flushing. This side effect typically occurs with moderate and high doses. Like with other side effects of Cialis, it usually fades as your body metabolizes the medication over the course of several hours.
Since facial flushing is a common ED medication side effect, switching to another drug such as Viagra or Levitra might not help the issue. If you’re prone to facial flushing, it’s best to discuss it with your healthcare provider.
Nasal Congestion
Like other ED medications, Cialis can cause nasal congestion. This side effect occurs in two to three percent of men who take Cialis and can occur with all dosages, from 5mg to 20mg taken as needed before sex.
Nasal congestion may occur due to tadalafil’s effects on blood vessels. When you use tadalafil, it may affect nitric oxide levels inside your nasal cavity, giving you a stuffy nose that could make breathing through your nostrils difficult.
As with many other Cialis side effects, nasal congestion tends to fade on its own as your body processes the medication.
While nasal congestion is a common side effect of all ED medications, switching from Cialis to shorter-acting drugs like Viagra or Levitra may make this side effect less long-lasting, as these medications remain active in your body for shorter periods of time.
Nasopharyngitis (Common Cold Symptoms)
Some men who use Cialis to treat ED report developing cold-like symptoms, or nasopharyngitis, after taking the medication.
As the common cold is a viral infection, it’s unlikely that Cialis is directly responsible for causing people to become sick. However, this medication’s effects on the soft tissue inside the nose and throat may cause some users to experience symptoms similar to those of a cold.
If you experience cold symptoms after taking Cialis, it could be due to the effects of the drug on your body’s soft tissue.
If these symptoms bother you, consider talking to your healthcare provider about adjusting your dosage or switching to a shorter-acting erectile dysfunction treatment.
Dizziness
Dizziness is a fairly uncommon side effect of Cialis. A small percentage of men who use Cialis report feeling dizzy and light-headed after taking this medication.
Other ED medications, such as Viagra and Levitra, may cause dizziness due to their effects on nitric oxide levels in the body.
If you feel dizzy after taking Cialis and don’t notice this side effect improving over time, it’s best to talk to your healthcare provider. They may suggest adjusting your dosage or switching to an alternative ED treatment.
Visual Disturbances
Several ED medications, including Cialis, are associated with visual disturbances such as color vision changes and blurred vision.
Although these side effects are temporary, they have the potential to affect your vision while the medication is active within your body. Because Cialis has a longer half-life than other ED drugs, this means that you could have some level of blurred vision or color issues for several hours.
If you experience blurred vision, difficulty seeing colors or other visual disturbances after taking Cialis, it’s important to talk to your healthcare provider.
These side effects could be treatable by adjusting your dosage or using a shorter-acting erectile dysfunction medication.
Reduced Blood Pressure
Does Cialis lower blood pressure? Like other PDE5 inhibitors, Cialis can produce a mild drop in your blood pressure levels.
In healthy men without heart disease or other cardiovascular health issues, this is not a problem and doesn’t cause any health issues.
In fact, lowered blood pressure is a common side effect of all FDA-approved erectile dysfunction medications. It’s typically caused by the dilating effects of these medications on blood vessels — an effect that can improve blood flow throughout certain areas of your body.
This drop in blood pressure can be potentially dangerous if you take certain medications to treat hypertension, such as nitrates.
If you have any cardiovascular health issues, make sure you tell your healthcare provider before you discuss CIalis or any other treatment for ED.
Pain in Limbs
In clinical trials, one to three percent of men who used Cialis reported experiencing pain in their limbs. This side effect was most common in men who were prescribed Cialis at a dosage of 10 or 20mg per day.
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Daily Cialis Side Effects
Cialis is available as a medication for use as needed and as a daily-use medication for treating erectile dysfunction.
In general, the adverse effects of daily-use Cialis are identical to those of Cialis when it’s taken as needed before sex.
However, because daily-use Cialis is prescribed at a lower dosage, some side effects appear to be less common.
For example, in clinical trials, 11 to 15 percent of men reported headaches from Cialis at a dose of five to 20mg. In comparison, only three to six percent of men who took Cialis every day at a dose of either 2.5mg or 5mg reported headaches.
Other side effects, such as dyspepsia and back pain, were also reported less frequently by men prescribed Cialis for daily use.
Our guide to daily Cialis provides more information about the advantages and disadvantages of using Cialis every day to treat ED.
Less Common, More Serious Cialis Side Effects
Cialis can cause serious side effects, although these are rare. Serious adverse effects of Cialis include priapism (a painful erection that may last for four hours or longer), optic nerve damage, hearing issues and interactions with other prescription medications.
Priapism
Priapism is a prolonged, often painful erection that lasts for four hours or longer. It’s a serious medical emergency that requires immediate attention to avoid damaging the erectile tissue in your penis.
Although it’s possible to experience a prolonged erection after using Cialis, this is an extremely uncommon side effect.
Considering millions of men use ED medications such as Cialis, it’s easy to see that the chance of experiencing priapism after using this type of medication is very low.
If you get a persistent and/or painful erection after using Cialis, it’s important to seek emergency medical care immediately. A healthcare professional can safely and effectively treat priapism to prevent any damage to your penile tissue.
Optic Nerve Damage
Cialis is one of several ED medications associated with optic nerve damage, which may cause or contribute to vision loss. Like priapism, this is an extremely rare side effect that only affects a tiny percentage of Cialis users.
The condition that Cialis is linked to is called nonarteritic anterior ischemic optic neuropathy, or NAION. It can develop when the blood supply to the optic nerve is reduced, potentially producing a reduction of the visual field.
Although exact data isn’t available, tadalafil was listed as one of several PDE5 inhibitors linked to rare reports of NAION in a study of sildenafil (Viagra) and optic nerve damage.
NAION appears to occur primarily in people with a pre-existing risk factor for eye damage, such as a small cup-to-disc ratio.
Hearing Issues
According to the FDA, several ED medications, including Cialis, have been linked to a decrease in hearing sensitivity or hearing loss in postmarketing reports.
Like priapism and damage to the optic nerve, cases of sudden hearing loss caused by Cialis are very uncommon. Evidence suggests that some of the reported cases of hearing loss associated with Cialis may be linked to underlying medical conditions.
If you take Cialis to treat ED and notice any changes in your hearing, it’s best to stop taking this medication and consult your healthcare provider as soon as you can.
Allergic Reaction to Cialis
Allergic reactions can occur with all medications, and Cialis is no exception. It’s possible to have an allergic reaction to the tadalafil that’s used in this medication, or to other, inactive ingredients that are used as part of the manufacturing process.
Common symptoms of an allergic reaction may include hives, rash, swelling that affects the lips, throat and tongue, and difficulty breathing or swallowing.
If you experience any of the above symptoms or other possible signs of an allergic reaction after taking Cialis, it's important to seek emergency medical help.
Other Rare Side Effects
Other uncommon side effects of Cialis include chest pain, ringing that affects your ears and skin issues, such as blistering and/or skin peeling.
Make sure to inform your healthcare provider if you develop these or other side effects after you use Cialis or other medications for ED.
Cialis Drug Interactions
As a PDE5 inhibitor, Cialis can interact with other medications, including medications prescribed to treat hypertension (high blood pressure), fungal infections, cardiovascular health issues such as coronary artery disease (CAD) and heart failure, as well as other medical conditions.
Interaction With Blood Pressure Medications
Tadalafil can interact with nitrates used to treat hypertension, angina and other heart conditions, causing abnormally low blood pressure that can lead to loss of consciousness, heart attack and even cardiac arrest (sudden death).
If you take nitrates like nitroglycerin, isosorbide dinitrate, isosorbide mononitrate or amyl nitrate to treat hypertension (high blood pressure) or angina (heart-related chest pain), you should not take Cialis.
In fact, you should not take any PDE5 inhibitors, such as sildenafil (Viagra), vardenafil (Levitra) or avanafil (Stendra), if you’re prescribed a nitrate medication.
All of these drugs interact with nitrates to cause a significant drop in blood pressure. In addition to nitrates used to treat cardiovascular conditions, ED medications can also interact with certain recreational drugs that contain nitrates, such as amyl nitrate “poppers.”
Do not use Cialis if you use any nitrate medications or recreational drugs, as this could result in severe side effects.
If you have heart disease, high blood pressure or any other cardiovascular health issue, inform your healthcare provider before using Cialis or any other medication to treat ED.
Interaction With Antifungal Medications
Cialis can interact with some oral antifungal medications used to treat issues such as ringworm and fungal nail infections. These medications, which inhibit the CYP3A4 enzyme, may increase your exposure to the effects of Cialis.
Oral antifungal medications include itraconazole and ketoconazole, among others. Some other medications that affect CYP3A4, such as the antibiotic erythromycin, and ingredients that affect CYP3A4, such as grapefruit or grapefruit juice, may also interact with Cialis.
You can read more about the relationship between grapefruit products and Cialis in our guide to Cialis and grapefruit interactions.
If you're prescribed these medications, your healthcare professional may adjust your dosage of Cialis to reduce your risk of developing side effects.
The FDA suggests taking Cialis at a maximum as-needed dosage of 10mg no more than once per 72 hours — or a daily dosage of 2.5mg — if you’re prescribed any other medication that inhibits CYP3A4.
Other Medications That May Interact With Cialis
Other medications may also interact with Cialis, including the following:
Ritonavir. This antiretroviral medication inhibits CYP3A4 and may increase the effects of Cialis in your body.
Alpha-blockers. Alpha-blockers can cause a drop in blood pressure when taken with Cialis. These medications are frequently prescribed to manage high blood pressure, benign prostatic hyperplasia (enlarged prostate) and other conditions.
Common alpha-blockers include Flomax® (tamsulosin HCl), Hytrin® (terazosin HCl), Cardura® (doxazosin mesylate), Uroxatral® (alfuzosin HCl), Jalyn® (dutasteride and tamsulosin HCl), Minipress® (prazosin HCl) and Rapaflo® (silodosin).
Other PDE5 inhibitors. Other PDE5 inhibitors, such as sildenafil (Viagra), vardenafil (Levitra) and avanafil (Stendra) should not be used with Cialis.
How to Avoid Cialis Side Effects
Cialis comes in tablet form, making it convenient to use as a treatment for ED. Although some online vendors advertise liquid versions of Cialis, these products are unregulated in the United States.
Currently, Cialis is available in two forms. The first is an as-needed version that’s prescribed for use before sexual activity, while the other is a daily-use pill.
If you're prescribed Cialis for use ‘as needed,’ you should take this medication around one hour before you plan to have sex.
Most men find that a normal dose of Cialis starts working within 30 to 60 minutes, and it can last for up to about 36 hours. This is significantly longer than other ED medications, such as Viagra (sildenafil), vardenafil (Levitra) or avanafil (Stendra).
Cialis can be used with or without food. It may take some time for you to find the right dosage of Cialis and time to use this medication for optimal sexual function.
Although there’s no simple, one-size-fits-all way to completely eliminate side effects from Cialis, there are several things that you can do to reduce your side effect risk.
Limit Your Alcohol Consumption
Drinking alcohol with Cialis can increase your risk of experiencing side effects. Alcohol can also negatively impact your sexual performance and level of sexual stimulation.
Try to limit your alcohol consumption while taking Cialis. The best way to do this is to avoid any alcohol consumption. However, if you typically drink alcohol while out on dates or just as part of your normal lifestyle, limiting your consumption to one to two small servings can also help.
Only Use Cialis as Prescribed
Most potential side effects of Cialis become more common at higher doses. Make sure to only use the dosage of Cialis that’s prescribed to you, even if you feel that it isn’t fully effective as a treatment for ED.
If you find it hard to get or maintain an erection after using Cialis, don’t adjust your dosage on your own. Instead, let your healthcare provider know about your concerns. They may increase your dosage or suggest other changes you can make to improve your erectile function.
Don’t Take Cialis More Than Once Per Day
Cialis is a long-lasting ED medication that’s not intended for use more than one time per day. A single dose of Cialis should produce a noticeable improvement in your erections that continues for up to 36 hours.
If you don’t notice any improvements after taking Cialis, do not take a second tablet. Instead, let your healthcare provider know. They may suggest adjusting your dosage or switching to another ED medication.
Cialis and Benign Prostatic Hyperplasia (BPH)
Although Cialis is widely known as a treatment for erectile dysfunction, it's also approved by the FDA for use as a treatment for benign prostatic hyperplasia (BPH, or enlarged prostate).
As a treatment for BPH, Cialis is typically taken daily. The potential side effects and interactions of Cialis are the same whether Cialis is used for ED or BPH, making it important to be aware of these effects before using this medication.
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The Bottom Line on the Side Effects of Cialis
It’s quite normal to experience one or several minor side effects from Cialis. However, serious side effects are uncommon.
If you’re prescribed Cialis for erectile dysfunction or benign prostatic hyperplasia and notice a concerning or problematic side effect, it’s important to talk to your healthcare provider as soon as you can.
They may recommend adjusting your Cialis dosage or making certain changes to the way you take this medication.
In some cases, your provider may recommend switching to another ED drug, such as sildenafil (the active ingredient in Viagra), vardenafil (Levitra) or avanafil (Stendra).
These medications are shorter-acting than Cialis, meaning any side effects you experience may fade away in a shorter amount of time.
We offer several FDA-approved ED medications online, following a consultation with a licensed healthcare provider who will determine if a prescription is appropriate.
You can learn more about the causes of and treatments for ED in our complete guide to erectile dysfunction.
9 Sources
Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references.
- Dhaliwal, A. & Gupta, M. (2022, May 20). PDE5 Inhibitors. StatPearls. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK549843/
- Tadalafil. (2022, February 15). Retrieved from https://medlineplus.gov/druginfo/meds/a604008.html
- Coward, R.M. & Carson, C.C. (2008, December). Tadalafil in the treatment of erectile dysfunction. Therapeutics and Clinical Risk Management. 4 (6), 1315-1330. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643112/
- CIALIS- tadalafil tablet, film coated. (2017, May). Retrieved from https://www.accessdata.fda.gov/spl/data/05dbd8b6-1b9d-436a-a67c-8a16713f753f/05dbd8b6-1b9d-436a-a67c-8a16713f753f.xml
- Bortolotti, M., et al. (2001, November). Effects of sildenafil on esophageal motility of normal subjects. Digestive Diseases and Sciences. 46 (11), 2301-2306. Retrieved from https://pubmed.ncbi.nlm.nih.gov/11713926/
- Questions and Answers for Cialis (tadalafil). (2015, August 13). Retrieved from https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/questions-and-answers-cialis-tadalafil
- Stockman, A., et al. (2007, June). The effect of sildenafil citrate (Viagra) on visual sensitivity. Journal of Vision. 7 (8), 4. Retrieved from https://pubmed.ncbi.nlm.nih.gov/17685811/
- Too much of a good thing: The 4-hour erection. (2008, September 11). Retrieved from https://www.nbcnews.com/healthmain/too-much-good-thing-4-hour-erection-1C9926694
- Gorkin, L., Hvidsten, K., Sobel, R.E. & Siegel, R. (2006, April). Sildenafil citrate use and the incidence of nonarteritic anterior ischemic optic neuropathy. International Journal of Clinical Practice. 60 (4), 500-503. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448698/
This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.
FAQs
What are the negative side effects of Cialis? ›
The most common side effects with Cialis are: headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects usually go away after a few hours. Men who get back pain and muscle aches usually get it 12 to 24 hours after taking Cialis.
What are the long term side effects of tadalafil? ›...
3.2 Safety and tolerability.
| Tadalafil (n=1173) | |
|---|---|
| Nausea | 25 (2.1) |
| Limb pain | 23 (2.0) |
CIALIS can cause your blood pressure to drop suddenly to an unsafe level if it is taken with any nitrate medication. You could get dizzy, faint or have a heart attack or stroke. Tell your healthcare provider that you take Cialis.
What foods to avoid when taking tadalafil? ›Do not eat grapefruit or drink grapefruit juice while you are using this medicine. Grapefruit and grapefruit juice may change the amount of this medicine that is absorbed in the body. Do not take other medicines unless they have been discussed with your doctor.
Does tadalafil affect the heart? ›The incidence rate of presumed thrombotic strokes in tadalafil studies (0.27 per 100 patient-years) is comparable to the expected rate in this patient population. The data presented herein suggest that tadalafil can be safely used by healthy subjects and by patients with cardiovascular diseases.
Is Cialis OK for your heart? ›Viagra and Cialis May Cut Risk of Early Death From Heart Disease by 25 Percent. A large new study shows that men who take erectile dysfunction medication are less likely to experience heart failure, stroke, and heart attack.
Does Cialis raise blood pressure? ›How does it affect blood pressure? Cialis can slightly lower blood pressure. This is not a problem for most men, but Cialis' effect on blood pressure is exaggerated if the Cialis is taken with a nitrate drug. Nitrates are one of the treatments doctors prescribe for angina.
Are there any long term side effects of Cialis? ›They found no serious adverse effects to long term use of tadalafil over the course of those two years. But most men will likely plan to take Cialis for more than two years — or at least hope to. And that's where things become ambiguous, because there aren't any long-term studies about adverse effects.
Is tadalafil hard on the kidneys? ›This medication is generally safe for use by men with kidney disease. However, it is important to follow your doctor's advice when taking tadalafil (Cialis) or other drugs used to treat erectile dysfunction.
Is it bad to take tadalafil every day? ›A daily dose of 5mg tadalafil can be safely used in the treatment of erectile dysfunction and LUTS, that prolongs the ejaculatory latency time.
How much tadalafil is safe daily? ›
Adults—10 milligrams (mg) as a single dose, no more than once a day, taken 30 minutes before you think sexual activity may occur. Your doctor may adjust your dose as needed. Children—Use is not recommended.
Does Cialis make you rock hard? ›Much like Viagra, Cialis relaxes the smooth muscles and arteries inside the penis. At the same time, it also increases blood flow to the penis. When aroused, this combination of relaxation and increased blood flow allows the penis to fill with blood, which results in an erection.
Why am I not getting hard on Cialis? ›But the main reason why Cialis and other medications don't work is the lack of sufficient blood flow to the penis no matter what the cause. For the most part, erections are all about having enough blood getting to the penis to result in an erection.
Why do bodybuilders take Cialis? ›What is known is that the medication, as a vasodilator, promotes better blood circulation throughout the body, not just in the penile region. With this, those who ingest the medicine, theoretically, would gain more energy and resistance.
Does caffeine affect tadalafil? ›Coffee and other sources of caffeine are not known to interact with Cialis. It should be safe to consume coffee and caffeine while taking this drug. According to one study , consuming caffeine may lower the risk of erectile dysfunction (ED).
How do you take tadalafil for best results? ›For erectile dysfunction, take 1 tablet at least 30 minutes before you want to have sex. If you are taking tadalafil for prostate enlargement, you can take your tablet in the morning or evening, but it's best to take it at the same time each day.
Is tadalafil hard on the liver? ›Hepatotoxicity. Despite fairly extensive use, tadalafil has been linked to only rare reports of serum aminotransferase elevations and clinically apparent liver injury. In a single case report, tadalafil was linked to cholestatic hepatitis arising within a few days of starting the medication.
Can tadalafil cause damage? ›Tadalafil was safe and well tolerated. Headache (15.8%), dyspepsia (11.8%), nasopharyngitis (11.4%), and back pain (8.2%) were the most common treatment-emergent adverse events.
Is tadalafil bad for prostate? ›Men with BPH usually have difficulty urinating, a decreased flow of urination, hesitation at the beginning of urination, and a need to get up at night to urinate. Tadalafil will make these symptoms less severe and reduce the chance that prostate surgery will be needed.
How safe is tadalafil? ›Generally, tadalafil is a safe drug but is not recommended to be taken if you have certain conditions or are taking specific medications that might interact with tadalafil. This is the same for all other phosphodiesterase type 5 inhibitors like Spedra, Viagra, Cialis, Levitra and sildenafil.
Is taking 5 mg of Cialis daily OK? ›
The drug comes in low-dose versions that can be taken daily. This means you can have sex at any time, rather than needing to take a pill from time to time as needed like other ED brands. The starting dose for daily-use Cialis is 2.5 milligrams (mg). If that doesn't work, you can increase your daily dose up to 5 mg.
What are the positive effects of tadalafil? ›Tadalafil Treatment Improves Inflammation, Cognitive Function, And Mismatch Negativity Of Patients With Low Urinary Tract Symptoms And Erectile Dysfunction | Scientific Reports.
How long does 6 mg of tadalafil last? ›Unlike Viagra, for instance, which can work for a few hours after the medication is taken, Tadalafil can be effective for up to 36 hours from just a single dose, according to the National Library of Medicine.
Does tadalafil increase size? ›found no difference in penile size between pre and postoperative measurements with the use of full dose PDE5-I on demand (8). We found a significant decrease in all penile measurements in control patients (not using Tadalafil) at 3rd postoperative month when compared with preoperative measurements (p = 0.001).
Can you stop taking Cialis abruptly? ›Also, do not stop taking this medicine without checking first with your doctor. This medicine comes with a patient information leaflet.
Does tadalafil affect sleep? ›Hours of undisturbed sleep (HUS) improved significantly after treatment with tadalafil, both overall and in new patients (Table 4). Urine volume voided/voiding at night improved numerically, but no significant difference was observed.
Is Cialis good for prostate? ›The chemical also relaxes muscle cells in the bladder and prostate. This may be why it eases the urinary symptoms of BPH. Cialis was approved for BPH after studies had found men who took 5 milligrams per day had improvements in both BPH and ED symptoms.
Is it safe to cut tadalafil in half? ›Do not break or split a Cialis tablet. Swallow it whole. Take the medicine at the same time each day, with or without food.
Can you build a tolerance to tadalafil? ›Tadalafil has a half‐life of 17.5 hours. In patients taking tadalafil more frequently than every 3–4 days, sustained plasma levels of tadalafil will be present and may be associated with an increased risk of tolerance.
Is 5mg of tadalafil strong enough? ›This means you take them at least 30mins before you plan to have sex, instead of the same time every day. The dose is the amount of the active drug ingredient 'tadalafil' inside each tablet. 5mg is the standard dose for Cialis Daily, and 10mg is the standard dose for on demand Cialis.
Does tadalafil affect urination? ›
Tadalafil 5 mg significantly increased maximum urinary flow vs placebo (median 1.1 vs 0.4 ml per second, p = 0.003).
Is tadalafil bad for blood pressure? ›Low dose tadalafil (5 mg daily) can improve blood pressure control and erectile function. The fact that PDE‐5 inhibitors can lower blood pressure and improve erectile function suggests that lowering blood pressure by itself does not cause ED and it is probably related to the antihypertensive medications.
Is 20 mg of tadalafil safe? ›According to the Food and Drug Administration (FDA) dosing guidelines for ED symptoms, the recommended dose for Cialis once daily is 2.5 mg to start and may be increased to 5 mg if needed. The recommended dose for as-needed Cialis is 10 mg and may be adjusted up or down to a maximum of 20 mg.
Can I take tadalafil 20 mg two days in a row? ›The maximum dose of Cialis that can be taken in a day is 20 mg. You should not take Cialis more than once a day. In clinical trials, Cialis helped people with ED symptoms for up to 36 hours after their dose. So if you're taking the medication only as needed, you shouldn't have to take it every day.
Is 40 mg of tadalafil too much? ›Official answer. The maximum recommended dose of Cialis is 20mg daily. Increasing the dose to 40mg might just increase the intensity of side effects and may not actually deal with the erectile dysfunction problem.
When is the best time to take tadalafil 20 mg? ›If you are taking tadalafil 10 mg or 20 mg tablets for erectile dysfunction: these tablets should only be taken before sexual activity - they are NOT for continuous daily use. You should take one tablet at least half an hour before you plan to have sex (it may still be effective up to 36 hours after taking the tablet).
At what age does a man stop ejaculating? ›While some men may experience premature ejaculation, others may experience difficulty ejaculating at all. While there is no definite age at which male ejaculation ceases, it has been suggested that it may happen when a man reaches his late 40s or early 50s.
Does Cialis keep you from ejaculating? ›Their study concluded that approximately 70 percent of men who used Cialis during sexual activity for 12 weeks were able to ejaculate most of the time and to reach orgasm, compared to 30 percent in the placebo group. Also, these benefits from the drug were seen despite the level of a man's ED severity.
How can I enhance my Cialis effect? ›- Take as directed. For as-needed dosing, take Cialis at least 30 minutes or more before sexual activity. ...
- Take as part of a lifestyle with physical activity. ...
- Communicate and stay relaxed.
Peak plasma concentrations of Cialis are reached within 30 minutes to six hours (average time two hours) of a dose. Effects of 'as needed' Cialis last for up to 36 hours. The recommended starting dose for once-daily Cialis for ED is 2.5mg; once daily Cialis for BPH, 5mg; and 'as needed' Cialis, 10mg.
Why is my Cialis 5mg daily not working? ›
The most common reasons why Cialis may not have worked are incorrect use or inadequate trial. It is important to understand that Cialis may not work after the first dose. It is advisable to try at least 8-10 doses before getting concerned about whether or not Cialis is working.
Can Cialis increase testosterone? ›In this study, we aimed to evaluate the effect of tadalafil 5 mg once daily on the level of testosterone in men with ED accompanied by the MetS. Our results showed that 5 mg tadalafil once daily improves ED by increasing TT levels in men.
Does Cialis change testosterone? ›Cialis does not interact with testosterone replacement therapy. Men experience no side effects from using Cialis while being treated for low testosterone with testosterone replacement therapy in the form of testosterone gel, testosterone injections, Testopel testosterone pellets or another treatment option.
Does Cialis give you a pump? ›From my research, the general consensus is that Cialis is a pretty effective pre-workout supplement. Tadalafil is capable of relaxing blood vessels and increasing blood flow in effect, which can enhance your overall energy and give you some pretty good pumps.
What is a good substitute for tadalafil? ›- Tadalafil.
- Staxyn.
- Caverject Impulse.
- Vardenafil.
- Alprostadil.
- Edex.
Tadalafil differs from other PDE5 inhibitors in that it has a significantly larger time frame of efficacy. Unlike Viagra, for instance, which can work for a few hours after the medication is taken, Tadalafil can be effective for up to 36 hours from just a single dose, according to the National Library of Medicine.
Do side effects go away with daily Cialis? ›Cialis Daily comes in tablet sizes of 2.5mg and 5mg, and can cause nausea, vomiting, diarrhoea, an allergic rash, facial flushing, headache and back pain. These side effects are uncommon and usually resolve within a few days.
How long does tadalafil stay in the system? ›Cialis can last up to 36 hours in the body but may last up to 72 hours in some cases. How long it lasts can vary. Your age, genetics, and if you have heart, liver, or kidney disease all affect how the drug works and how long Cialis stays in your body. You may need dose adjustments to avoid side effects.
What is the best pill to stay hard longer? ›- Sildenafil (Viagra). This medication is most effective when taken on an empty stomach one hour before sex. ...
- Vardenafil (Levitra, Staxyn). This medication also is most effective when taken one hour before sex and can be taken with or without food. ...
- Tadalafil (Cialis). ...
- Avanafil (Stendra).
- Amore 36 - Chemo Biological [Tadalafil] Strength. ...
- Erectalis - Cipla [Tadalafil] Strength. ...
- Forzest - Ranbaxy [Tadalafil] Strength. ...
- Golmal - Jpee Drugs [Tadalafil] Strength. ...
- Manforce More - Mankind [Tadalafil] Strength. ...
- Megalis - Macleods [Tadalafil] Strength. ...
- Oneaid - BMW [Tadalafil] Strength. ...
- Popup - AHPL [Tadalafil] Strength.
What is stronger Cialis or tadalafil? ›
Generic Cialis, or Tadalafil, is the same as Cialis in terms of its active ingredient (tadalafil), its effectiveness and side effects. The difference you may see is in the cost, with generic medicines tending to be less expensive.
Is 5mg of tadalafil enough? ›The dose is the amount of the active drug ingredient 'tadalafil' inside each tablet. 5mg is the standard dose for Cialis Daily, and 10mg is the standard dose for on demand Cialis.
Does tadalafil make harder? ›By controlling the enzyme, tadalafil helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. Without physical action to the penis, such as that occurring during sexual intercourse, tadalafil will not work to cause an erection.
When do Cialis side effects peak? ›Peak plasma concentrations of Cialis are reached within 30 minutes to six hours (average time two hours) of a dose. Effects of 'as needed' Cialis last for up to 36 hours. The recommended starting dose for once-daily Cialis for ED is 2.5mg; once daily Cialis for BPH, 5mg; and 'as needed' Cialis, 10mg.
Is Cialis good for the heart? ›Viagra and Cialis May Cut Risk of Early Death From Heart Disease by 25 Percent. A large new study shows that men who take erectile dysfunction medication are less likely to experience heart failure, stroke, and heart attack.
Can I take tadalafil for life? ›A 2004 clinical trial published in the Journal of European Urology followed more than 1,000 men using various dosages of tadalafil for up to 24 months. They found no serious adverse effects to long term use of tadalafil over the course of those two years.
Does tadalafil keep you from ejaculating? ›Conclusions: Tadalafil 5 mg once daily significantly improved ejaculation and orgasm, intercourse and overall satisfaction, and erectile function.
What is the peak time for tadalafil? ›Most men feel the benefit of tadalafil after 30 minutes. 52% of patients can have successful sexual intercourse within 30 minutes of taking tadalafil. After 2 hours, the maximum concentration of the drug is in the bloodstream.